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Dualvir-Main

Dualvir-Main
Dualvir-Main
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Product Code : 225
Product Description

Dualvir-Main

Ledipasvir & Sofosbuvir

Ledipasvir is an inhibitor of the HCV NS5A protein, which is required for viral replication. Resistance selection in cell culture and cross-resistance studies indicate ledipasvir targets NS5A as its mode of action. Sofosbuvir is an inhibitor of the HCV NS5B RNA-dependent RNA polymerase, which is required for viral replication. Sofosbuvir is a nucleotide prodrug that undergoes intracellular metabolism to form the pharmacologically active uridine analog triphosphate which can be incorporated into HCV RNA by the NS5B polymerase and acts as a chain terminator.


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