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Dextromethorphan HCl, Pseudoephedrine HCl & Triprolidine HCl
Freecof is the combination of three active ingredients, Dextromethorphan HBr, Pseudoephedrine HCl & Triprolidine HCl. Dextromethorphan HBr has an antitussive action. It controls coughs by depressing the medullary cough centre. It is used to suppress dry or painful cough. It is useful for clearing mucus, dust and other particles from the throat and lungs. Pseudoephedrine HCl has a sympathomimetic activity and is an effective upper respiratory decongestant. It acts by stimulating alpha adrenergic receptors. In the lining of the nose and sinuses, pseudoephedrine acts on receptors in the muscles of the blood vessel walls, causing them to contract and therby decreases blood flow to the lining of the nose and sinuses. By decreasing blood flow, fluid congestion in the nose and sinuses is reduced. Triprolidine is a sedating antihistamine which acts on histamine H1 receptors. It blocks the action of histamine, preventing dilatation of blood vessels, reducing redness and swelling. Therefore, this syrup is used to relieve the symptoms of colds and flu, such as nasal congestion, cough and runny nose, where these are associated with a dry cough.