Cookie Img Back to top
Your reliable supplier of generic medications
Home » Products » Antidiabetic Hypoglycemic Drugs » Gluvan 28S Main

Gluvan 28S Main

Gluvan 28S Main
Gluvan 28S Main
Send Inquiry
Product Code : 128
Product Description

Gluvan 28S Main


Vildagliptin is a potent and selective dipeptidyl peptidase-4 (DPP-4) inhibitor. It rapidly and completely inhibits DPP-4 activity and thus increases the levels of two incretin hormones GLP-1 (glucagon-like peptide-1) and GIP (glucose-dependent insulinotropic polypeptide). Thus it enhances the sensitivity of beta cells to glucose, resulting in improved glucose-dependent insulin secretion. It also enhances the sensitivity of alpha cells to glucose by increasing endogenous GLP-1 levels, resulting in reduced glucagon secretion. The increase in the insulin/glucagon ratio during hyperglycemia due to increased incretin hormone levels results in a decrease in fasting and postprandial hepatic glucose production, leading to reduced glycemia.