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Neurovan-50

Neurovan-50
Neurovan-50
Product Code : 332
Product Description

Neurovan-50

Pregabalin

Pregabalin is an analog of the neurotransmitter gamma-aminobutyric acid (GABA). It has analgesic and anticonvulsant activity. Pregabalin binds to an auxiliary subunit ( 2 protein) of voltage-gated calcium channels in the central nervous system and reduces calcium influx into the nerve terminals. It decreases the release of neurotransmitters such as glutamate, noradrenaline and Substance P. It also increases neural GABA levels by producing a dose dependent increase in Glutamic Acid Decarboxylase (GAD) activity. GAD is the enzyme that converts the excitatory glutamate into inhibitory GABA in a single step. Binding of Pregabalin to the 2 site is required for analgesic and anticonvulsant activity.
 


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