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Ambroxol is a metabolite of bromhexine. It is an expectoration improver and mucolytic agent used in the treatment of acute and chronic disorders characterized by the production of excess or thick mucus. It causes the formation of qualitatively different mucus of lower viscosity by the mucus-secreting cells and thus leads to a liquefication of mucus in the lumen of the respiratory tract. Expectoration of mucus is facilitated and breathing is eased remarkably. Ambroxol also has anti-inflammatory properties owing to the inhibitory effect on the production of cellular cytokines and arachidonic acid metabolites. In patients with COPD it traditionally improves airway patency.