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Product Code : 187
Product Description

Notens Tab


Bromazepam is a benzodiazepine with anxiolytic and sedative properties, which are of value in the symptomatic relief of pathological anxiety in psychoneurotic patients. The absolute bioavailability of unchanged, orally administered bromazepam is 60%, and peak blood levels are achieved within 2 hours after administration. On average, 70% of bromazepam is bound to plasma proteins. Bromazepam is metabolized in the liver, and has an elimination half-life of 20 hours (the half-life may be longer in elderly patients). The metabolites are excreted in the urine as conjugated form. Bromazepam binds to specific site on the GABA, an important inhibitory neurotransmitters in the CNS, which acts by opening chloride ion channel into the cells.