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Glucosamine sulfate & Chondroitin sulfate
Glucosamine, an amino sugar, is the building block for certain glycosaminoglycans. In vitro, it has been shown to stimulate proteoglycan synthesis by human chondrocytes. It has also some innate anti-inflammatory properties, independent of prostaglandin synthesis. Glucosamine is also involved in the formation of nails, tendons, skin, eyes, bones, ligaments and other connective tissues in the body. Glucosamine is absorbed rapidly from the intestine, and transported to the connective tissues. It helps in the restoration of damaged joint tissue in osteoarthritis.
Chondroitin sulphate is a glycosaminoglycan and is a main constituent of proteoglycans. Like glucosamine, it has been shown to stimulate proteoglycan synthesis by human chondrocytes. Chondroitin sulphate also has some innate anti-inflammatory properties.