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Tenoxicam is a non-steroidal anti-inflammatory drug (NSAID) with anti-inflammatory, analgesic and antipyretic properties. It also inhibits platelet aggregation. Tenoxicam inhibits prostaglandin biosynthesis. In-vitro tests of leukocyte peroxidase suggest that tenoxicam may act as a scavenger for active oxyegen at the site of inflammation. Tenoxicam is a potent in-vitro inhibitor of human metalloproteinases, which induce cartilage breakdown. These pharmacological effects explain, at least in part, the therapeutic benefit of tenoxicam in the treatment of painful inflammatory and degenerative disorders of the musculoskeletal system. Antipyretics may occur by central action on the hypothalamus, resulting in peripheral dilation, increased cutaneous blood flow, and subsequent heat loss.